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bc10: A novel human bladder cancer‐associated protein with a conserved genomic structure downregulated in invasive cancer

24 Jan 2002

Abstract excerpt

To identify novel genes that may be associated with the invasive phenotype of bladder cancer, we compared the mRNA expression profiles of fresh noninvasive (grade II, Ta) and invasive (grade III, T2-T4) human transitional cell carcinomas (TCCs) by mRNA differential display. Using this approach, we isolated a novel gene, designated bc10 (bladder cancer, Mr 10 kDa) that was exclusively expressed in the noninvasive...

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PMID: 11920613
DOI: 10.1002/ijc.10244

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