Article
Identification of new splice variants and differential expression of the human kallikrein 10 gene, a candidate cancer biomarker.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2000
Yousef George M, White Nicole M A, Michael Iacovos P, Cho Jane Chan-Kyung, Robb John Desmond, Kurlender Lisa, Khan Saba, Diamandis Eleftherios P
Abstract excerpt
The human kallikrein gene 10 (KLK10) is a member of the kallikrein gene family on chromosome 19q13.4. This gene was identified by its downregulation in breast cancer, and preliminary evidence suggests that it may act as a tumor suppressor. A computer-based analysis was performed on EST and SAGE clones from the Cancer Genome Anatomy Project and other databases. Experimental verification of differential expression...
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