Article
Erythropoietin stimulates vasculogenesis in neonatal rat mesenteric microvascular endothelial cells.
Pediatric research - 1 Apr 2002
Ashley Richard A, Dubuque Suzanne H, Dvorak Bohuslav, Woodward Suann S, Williams Stuart K, Kling Pamela J
Abstract excerpt
Human breast milk is a rich source of growth factors, including erythropoietin (Epo), the endogenous hormonal stimulant of erythropoiesis. Recombinant human Epo (rhEpo) has been shown to stimulate 1) angiogenesis, the process of new blood vessel growth from preexisting vessels; 2) vasculogenesis, tubule formation from single-cell suspensions; and 3) endothelial cell proliferation in immortalized endothelial cells...
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