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Article

Solitary functioning kidney and diverse genital tract malformations associated with hepatocyte nuclear factor-1beta mutations.

Kidney international - 1 Apr 2002

Bingham Coralie, Ellard Sian, Cole Trevor R P, Jones Katrin E, Allen Lisa I S, Goodship Judith A, Goodship Timothy H J, Bakalinova-Pugh Daniela, Russell Gavin I, Woolf Adrian S, Nicholls Anthony J, Hattersley Andrew T

Abstract excerpt

BACKGROUND: Renal tract malformations are, on occasion, associated with uterine malformations. The transcription factor hepatocyte nuclear factor (HNF)-1beta is expressed from the earliest stages of development of the Wolffian duct, the mesonephros and metanephros, and the Müllerian ducts in the mouse. In adult mice HNF-1beta is expressed in the kidney tubules, collecting ducts, and in the oviducts and uterus in...

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Identifiers

PMID: 11918730
DOI: 10.1046/j.1523-1755.2002.00272.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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