Article
Predicted structures of two proteins involved in human diseases.
Cell biochemistry and biophysics - 1 Jan 2001
Zhou H X, Wang G
Abstract excerpt
Structures of 79 proteins involved in human diseases were predicted by sequence alignments with structural templates. The predicted structures for ALDP and CSA, proteins responsible for adrenoleukodystrophy and the Cockayne syndrome, respectively, were analyzed to elucidate the molecular basis of disease mutations. In particular we positioned residue P484 of ALDP in the homodimer interface. This positioning is...
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