Article
The relationship between genotype and exercise tolerance in children with cystic fibrosis.
American journal of respiratory and critical care medicine - 15 Mar 2002
Selvadurai Hiran C, McKay Karen O, Blimkie Cameron J, Cooper Peter J, Mellis Craig M, Van Asperen Peter P
Abstract excerpt
The relationship between fitness and genotype in children with cystic fibrosis (CF) and at least one copy of the DeltaF508 mutation was examined. Genotype was classified according to the second CF mutation. Fitness was measured by peak aerobic capacity (using a modified Bruce protocol during treadmill exercise) and anaerobic power (using the Wingate test on a cycle ergometer). The class of cystic fibrosis...
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