Article
Diversity in the oesophageal phenotypic response to gastro-oesophageal reflux: immunological determinants.
Gut - 1 Apr 2002
Fitzgerald R C, Onwuegbusi B A, Bajaj-Elliott M, Saeed I T, Burnham W R, Farthing M J G
Abstract excerpt
BACKGROUND AND AIMS: Approximately 10% of adults experience gastro-oesophageal reflux symptoms with a variable oesophageal response. A total of 60% have no endoscopic abnormality, 30% have oesophagitis, and 10% have Barrett's oesophagus. We investigated whether the inflammatory cell infiltrate and cytokine profiles of these clinical phenotypes merely vary in severity or are fundamentally different. METHODS:...
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