Article
Regulatory role of SGT1 in early R gene-mediated plant defenses.
Science (New York, N.Y.) - 15 Mar 2002
Austin Mark J, Muskett Paul, Kahn Katherine, Feys Bart J, Jones Jonathan D G, Parker Jane E
Abstract excerpt
Animal SGT1 is a component of Skp1-Cullin-F-box protein (SCF) ubiquitin ligases that target regulatory proteins for degradation. Mutations in one (SGT1b) of two highly homologous Arabidopsis SGT1 genes disable early plant defenses conferred by multiple resistance (R) genes. Loss of SGT1b function in resistance is not compensated for by SGT1a. R genes differ in their requirements for SGT1b and a second resistance...
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