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Ex-vivo short-term culture and developmental assessment of Plasmodium vivax

1 Nov 2001

Abstract excerpt

A simple reproducible method for short-term ex-vivo Plasmodium vivax culture is presented in which glucose, ascorbic acid, thiamine, hypoxanthine, and 50% human AB+ serum are added to the standard P. falciparum in-vitro culture medium. Culture of freshly obtained blood samples from patients with acute vivax malaria with > 0.5% parasitaemia resulted in > 95% complete schizogony. Culture could be continued for 5-6...

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PMID: 11816444
DOI: 10.1016/s0035-9203(01)90113-0

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