Article
High prevalence of the G101W germline mutation in the CDKN2A (P16(ink4a)) gene in 62 Italian malignant melanoma families.
American journal of medical genetics - 22 Jan 2002
Mantelli Michela, Barile Monica, Ciotti Paola, Ghiorzo Paola, Lantieri Francesca, Pastorino Lorenza, Catricalà Caterina, Torre Gabriella Della, Folco Ugo, Grammatico Paola, Padovani Laura, Pasini Barbara, Rovini Dario, Queirolo Paola, Rainero Maria Luisa, Santi Pier Luigi, Sertoli Roberto M, Goldstein Alisa M, Bianchi-Scarrà Giovanna
Abstract excerpt
CDKN2A germline mutation frequency estimates are commonly based on families with several melanoma cases. When we started counseling in a research setting on gene susceptibility analysis in northern and central Italy, however, we mostly found small families with few cases. Here we briefly characte...
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