Article
[A study on the mechanism of the resistance of Shigellae to fluoroquinolones].
Zhonghua nei ke za zhi - 1 Aug 1999
Ding J, Ma Y, Gong Z, Chen Y
Abstract excerpt
OBJECTIVE: To study the mechanism of the resistance of Shigellae to fluoroquinolones. METHODS: A total of 157 clinical isolates were collected. Antibiotic susceptibility testing, reserpine reverse reaction and plasmid conjugation experiment were performed. Accumulation of norfloxacin by shigellae was determined. The N-terminal coding region of gyrA gene was amplified by polymerase chain reaction (PCR), cloned and...
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