Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Letting the genome out of the bottle: prospects for new drug development.

Annals of the New York Academy of Sciences - 1 Dec 2001

Young D

Abstract excerpt

Use of the information gained from sequencing the Mycobacterium tuberculosis genome will enable scientists to accelerate the development of reagents for improved tuberculosis control. Cloning and expressing genes encoding the enzymes involved in cell-wall biosynthesis will provide the tools for screening millions of novel compounds. Cell wall inhibitors will be mainly useful in treating resistant disease, but...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antitubercular Agents
Share to Drug Design
Share to Genome, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mycobacterium tuberculosis

Share to Phenotype

Share to Tuberculosis, Multidrug-Resistant

Source

Identifiers

PMID: 11795407
DOI: 10.1111/j.1749-6632.2001.tb11372.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Letting the genome out of the bottle: prospects for new drug development.PMID 11795407Read ↗

Future directions in the development of new antitubercular drugs. Where do we go from here?Semantic proximity Read ↗

Target Identification in Anti-Tuberculosis Drug DiscoverySemantic proximity Read ↗

Antibiotics and resistance: the two-sided coin of the mycobacterial cell wallSemantic proximity Read ↗

Toward a new therapy for tuberculosis.Semantic proximity Read ↗

Mycobacterial Membrane Protein Large 3 (MmpL3) Inhibitors: A Promising Approach to Combat TuberculosisSemantic proximity Read ↗

Tuberculosis drug discovery in the CRISPR eraSemantic proximity Read ↗

Tuberculosis drug discovery in the post‐post‐genomic eraSemantic proximity Read ↗

Cell Surface Biosynthesis and Remodeling Pathways in Mycobacteria Reveal New Drug TargetsSemantic proximity Read ↗

<scp>TB</scp> drug development: immunology at the tableSemantic proximity Read ↗

Mycobacterial cell wall biosynthesis: a multifaceted antibiotic targetSemantic proximity Read ↗

Development of Mycobacterium tuberculosis whole cell screening hits as potential antituberculosis agents.Semantic proximity Read ↗

Current status and future development of antitubercular chemotherapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.