Article
Friedreich's ataxia: clinical and molecular study of 25 Brazilian cases.
Revista do Hospital das Clinicas - 1 Jan 2000
Albano L M, Zatz M, Kim C A, Bertola D, Sugayama S M, Marques-Dias M J, Kok F, Ferraretto I, Rosemberg S, Cocozza S, Monticelli A
Abstract excerpt
INTRODUCTION: Friedreich's ataxia is a neurodegenerative disorder whose clinical diagnostic criteria for typical cases basically include: a) early age of onset (< 20 or 25 years), b) autosomal recessive inheritance, c) progressive ataxia of limbs and gait, and d) absence of lower limb tendon reflexes. METHODS: We studied the frequency and the size of expanded GAA and their influence on neurologic findings, age at...
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