Article
Low ileal interleukin 10 concentrations are predictive of endoscopic recurrence in patients with Crohn's disease.
Gut - 1 Jan 2002
Meresse B, Rutgeerts P, Malchow H, Dubucquoi S, Dessaint J P, Cohard M, Colombel J F, Desreumaux P
Abstract excerpt
BACKGROUND: Endoscopic recurrence after surgery in Crohn's disease is frequent and unpredictable. Abnormal intestinal production of pro- (interleukin (IL)-1 beta, tumour necrosis factor alpha (TNF-alpha)) and anti- (IL-10) inflammatory cytokines has been associated with severe outcome in experimental models of colitis. PATIENTS AND METHODS: We evaluated if ileal TNF-alpha, IL-1 beta, or IL-10 mRNA levels measured...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
