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Article

Validity of the Hfm transgenic mouse as a model for hemifacial microsomia.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Jan 2002

Cousley Richard, Naora Hiroyuki, Yokoyama Minesuke, Kimura Minoru, Otani Hiroki

Abstract excerpt

OBJECTIVE: Our comprehension of hemifacial microsomia (HFM) has been hindered by its diverse phenotype and unclear etiopathogenesis. The conventional view has been that HFM's facial defects result from embryonic hemorrhages in the region of the first and second branchial arches. A more recent model based on a transgenic mutation of a locus termed Hfm (B1 to B3 on chromosome 10) appears to provide an insight into...

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Identifiers

PMID: 11772174
DOI: 10.1597/1545-1569_2002_039_0081_vothtm_2.0.co_2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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