Article
Real-time quantitative polymerase chain reaction: a potential tool for genetic analysis in neuropathology.
Brain pathology (Zurich, Switzerland) - 1 Jan 2002
Aldape Kenneth, Ginzinger David G, Godfrey Tony E
Abstract excerpt
Since its introduction in the early- to mid-1980s, the polymerase chain reaction (PCR) has been modified and optimized for an increasing number of applications. Early on, the focus was on the amplification of a specific nucleic acid template into quantities amenable to identification and experimental manipulation. While this remains an important application, recent technology has allowed the use of PCR to...
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