Article
Isolated anti-HBc in chronic hepatitis C predicts a poor response to interferon treatment.
Journal of medical virology - 1 Dec 2001
Sagnelli E, Coppola N, Scolastico C, Mogavero A R, Stanzione M, Filippini P, Felaco F M, Piccinino F
Abstract excerpt
The sustained response to interferon-alpha treatment was evaluated in 147 anti-HCV/HCV-RNA-positive, HBsAg-negative, chronic hepatitis patients, according to HCV genotypes and the presence or absence of anti-HBs and anti-HBc. These patients had been included in a controlled study on the safety, tolerability, and efficacy of three types of interferon-alpha given at a dose of 3 MU three times weekly for 52 weeks....
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