Article
Persistent Productive Epstein‐Barr Virus Replication in Normal Epithelial Cells In Vivo
15 Dec 2001
Abstract excerpt
Productive Epstein-Barr virus (EBV) replication characterizes hairy leukoplakia, an oral epithelial lesion typically occurring in individuals infected with human immunodeficiency virus (HIV). Serial tongue biopsy specimens were obtained from HIV-infected subjects before, during, and after valacyclovir treatment. EBV replication was detected by Southern hybridization to linear terminal EBV genome fragments,...
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