Article
Characterization of bradykinin receptors in a human osteoblastic cell line.
Regulatory peptides - 15 Jan 2002
Brechter Anna Bernhold, Lerner Ulf H
Abstract excerpt
Bradykinin receptor subtypes linked to prostaglandin release have been assessed in a human osteosarcoma cell line with osteoblastic phenotype (MG-63). Bradykinin (BK; 1 micromol/l) caused a burst of prostaglandin E(2) release that was maximal at 10 min. When the effect on the burst of PGE(2) and PGI(2) release by a variety of kinins and kinin analogues was assessed, the following rank order of response was found:...
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