Abnormal lipoprotein metabolism and reversible female infertility in HDL receptor (SR-BI)–deficient mice

Abstract excerpt

Human female infertility, which in many cases is of unknown etiology, is a significant medical problem (1, 2). The influence of abnormal lipoprotein metabolism on female infertility has not been thoroughly explored, despite observations suggesting a potential role for plasma lipoproteins, especially HDL (3-5). Lipoproteins transport between tissues a number of lipids (e.g., cholesterol, steroid hormones, and...

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