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Article

Therapeutic application of chimeric RNA/DNA oligonucleotide based gene therapy.

Expert opinion on biological therapy - 1 Jan 2001

Lai L W, Lien Y H

Abstract excerpt

Chimeric RNA/DNA oligonucleotides, or chimera, have emerged as a breakthrough technology for treating genetic disorders. Chimera have been shown to induce correction of point mutations in several genetic disease models without utilising the viral vectors. Recent studies of chimera-based gene therapy in genetic disease models are reviewed. Chimera were delivered intravenously, intramuscularly, intradermally, or...

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Identifiers

PMID: 11727546
DOI: 10.1517/14712598.1.1.41

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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