Article
Intracellular pH, intrauterine growth and the insulin resistance syndrome.
Clinical physiology (Oxford, England) - 1 Nov 2001
Pinkney J H, Vernon P, Carstensen E, Gillies S, Phillips D I, Yudkin J S
Abstract excerpt
Defects of both sodium-hydrogen exchange (NHE) and sodium-lithium countertransport (SLC) have been described in subjects at increased risk of coronary heart disease (CHD). Sodium transport is linked to the regulation of cell volume, intracellular pH and cell growth, which may explain aspects of this association. However, impaired growth in early life is also linked to adult CHD, and 'programmed' alterations of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
