Article
Lipoprotein lipase gene mutations and the genetic susceptibility of preeclampsia.
Hypertension (Dallas, Tex. : 1979) - 1 Nov 2001
Kim Y J, Williamson R A, Chen K, Smith J L, Murray J C, Merrill D C
Abstract excerpt
In the pathogenesis of preeclampsia, endothelial cell activation or dysfunction is a central theme, and marked dyslipidemia may contribute to endothelial cell dysfunction. The objective of this study was to evaluate the association between preeclampsia and mutations within the lipoprotein lipase (LPL) gene. DNA was extracted from whole blood or cheek swabs of 250 preeclamptic patients, 265 control subjects, and...
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