Article
Acute HIV infection: impact on the spread of HIV and transmission of drug resistance.
AIDS (London, England) - 23 Nov 2001
Yerly S, Vora S, Rizzardi P, Chave J P, Vernazza P L, Flepp M, Telenti A, Battegay M, Veuthey A L, Bru J P, Rickenbach M, Hirschel B, Perrin L
Abstract excerpt
OBJECTIVE: To assess the impact of primary HIV infection (PHI) on the spread of HIV and the temporal trends in transmission of HIV drug resistance between 1996 and 1999 in Switzerland. METHODS: Sequencing of the genes for reverse transcriptase (RT) and protease was performed for 197 individuals with documented PHI. Phylogenetic analyses were confronted with epidemiological data. RESULTS: Significant clustering...
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