Article
Impaired expression of the plastidic ferrochelatase by antisense RNA synthesis leads to a necrotic phenotype of transformed tobacco plants.
The Plant journal : for cell and molecular biology - 1 Oct 2001
Papenbrock J, Mishra S, Mock H P, Kruse E, Schmidt E K, Petersmann A, Braun H P, Grimm B
Abstract excerpt
Protoporphyrin IX is the last common intermediate of tetrapyrrole biosynthesis. The chelation of a Mg2+ ion by magnesium chelatase and of a ferrous ion by ferrochelatase directs protoporphyrin IX towards the formation of chlorophyll and heme, respectively. A full length cDNA clone encoding a ferrochelatase was identified from a Nicotiana tabacum cDNA library. The encoded protein consists of 497 amino acid...
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