Article
[Lip-jaw-palate clefts. Heterogenous disease pictures].
Mund-, Kiefer- und Gesichtschirurgie : MKG - 1 Sept 2001
Kunstmann E, Radtke J, Epplen J T
Abstract excerpt
BACKGROUND: Orofacial clefts are congenital structural deficits involving the lip with or without the palate. The genetic origins of orofacial clefts have been considered as heterogeneous for a long time. Non-syndromatic clefts are based on complex traits. DISCUSSION: The different approaches towards the genetics of this multifactorial disease are discussed and the consequences for genetic counselling for...
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