Article
Congenital von Willebrand disease type 3: clinical manifestations, pathophysiology and molecular biology.
Best practice & research. Clinical haematology - 1 Jun 2001
Eikenboom J C
Abstract excerpt
von Willebrand disease type 3 is the most severe form of this condition. Patients present with a moderate-to-severe bleeding tendency. The plasma von Willebrand factor level in these patients is very low or undetectable. Although rare, von Willebrand disease type 3 is of major interest because of its severe clinical presentation, the need for replacement therapy and the risk of occurrence of alloantibodies after...
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