Article
Availability and characterization of transgenic and knockout mice with behavioral manifestations: where to look and what to search for.
Behavioural brain research - 1 Nov 2001
Anagnostopoulos A V, Sharp J J, Mobraaten L E, Eppig J T, Davisson M T
Abstract excerpt
Mice altered by transgenesis or gene targeting ("knockouts") have increasingly been employed as alternative effective tools in elucidating the genetic basis of neurophysiology and behavior. Standardization of specific behavioral paradigms and phenotyping strategies will ensure that these behavioral mouse mutants offer robust models for evaluating the efficacy of novel therapeutics in the treatment of hereditary...
Topics
- Animals
- Behavior, Animal
- Brain
- Catalogs as Topic
- Databases, Genetic
- Genetics
- Internet
- Mice
- Mice, Knockout
- Mice, Transgenic
- Phenotype
