Article
Mutations in mammalian cells induced by heavy charged particles: an indicator for risk assessment in space.
Radiation research - 1 Nov 2001
Kiefer J, Schmidt P, Koch S
Abstract excerpt
Induction of mutations at the HPRT locus in V79 Chinese hamster cells by heavy charged particles is reviewed. A unique dependence of mutation induction cross sections on LET or any other physical parameter of the particles cannot be found. There is, however, a general trend showing an increase up to about 100 keV/microm and an indication of a saturation with higher LET. An empirical expression is given...
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