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Article

Axon damage in CMT due to mutation in myelin protein P0.

Neuromuscular disorders : NMD - 1 Nov 2001

Hanemann C O, Gabreëls-Festen A A, De Jonghe P

Abstract excerpt

We describe a family carrying the Thr148Met mutation in the P0 gene. Contrary to other neuropathies caused by myelin gene defects, no demyeliantion could be found in our biopsies. Based on follow up examinations, extensive morphometry and immunohistochemical analysis we suggest that the mild hypomyelination documented in our family secondarily causes axonal degeneration and axonal loss of large and small fibers...

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Source

Identifiers

PMID: 11595518
DOI: 10.1016/s0960-8966(01)00229-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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