Article
HLA antigens in alkaptonuric patients.
Panminerva medica - 1 Sept 2001
Aliberti G, Proietta M, Pulignano I, Tamburro M L
Abstract excerpt
BACKGROUND: In alkaptonuric patients a disabling ochronotic arthropathy develops, due to the deposit of a pigmented polymer of homogentisic acid. Since in inherited diseases the clinical expressions may be multifactorial, involving genetic and environmental factors, where the HLA system may play a role, we studied HLA antigens in ochronotic patients. METHODS: The study was carried out in 21 members of three...
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