Article
Reactivation of latently infected hepatitis B virus in a leukemia patient with antibodies to hepatitis B core antigen.
Journal of gastroenterology - 1 Sept 2001
Marusawa H, Imoto S, Ueda Y, Chiba T
Abstract excerpt
A 66-year-old man with chronic B-cell leukemia who had antibody to hepatitis B core antigen (anti-HBc) but not hepatitis B surface antigen (HBsAg) suffered from lethal hepatitis caused by hepatitis B virus (HBV) reactivation. He initially lacked circulating viral genomes in his sera and did not have a past history of liver dysfunction. In this patient, the immunosuppressive condition introduced by disease...
Topics
- Aged
- Antibodies
- Antineoplastic Combined Chemotherapy Protocols
- Cyclophosphamide
- Fatal Outcome
- Hepatitis B
- Hepatitis B Core Antigens
- Hepatitis B Surface Antigens
- Hepatitis B virus
- Humans
- Immunosuppression Therapy
- Immunosuppressive Agents
- Leukemia, B-Cell
- Male
- Mutation
- Polymerase Chain Reaction
- Recurrence