Article
[The genetics of labio-palatal clefts].
Revue de stomatologie et de chirurgie maxillo-faciale - 1 Jun 2001
Rival J M, David A
Abstract excerpt
Labial and/or palatine clefts are an interest in example of the interaction between genetic and environmental factors. The OFC1 gene, localized on 6p24.3 would play a primary role in the development of labial and/or palatine clefts while the OFC2 (2p13), OFC3 (19p13.2) and RARA (17q21.1) would play a role in modifying genetic susceptibility. Different environmental, nutritional and toxic factors (alcohol,...
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