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Article

Immunomodulation by human seminal plasma: a benefit for spermatozoon and pathogen?

1 Oct 1997

Abstract excerpt

The immunosuppressive effect of human seminal plasma and its implications for sperm survival are reviewed. Human semen contains high concentrations of prostaglandins that can effect a cytokine-mediated switch away from a cell-mediated immune response. This effect on antigen presenting cells would induce a state of non-responsiveness to sperm antigens in the female reproductive tract. It is postulated that the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 9402282
DOI: 10.1093/oxfordjournals.humrep.a019559

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