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Article

Identical mutations in NOG can cause either tarsal/carpal coalition syndrome or proximal symphalangism.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jan 2000

Dixon M E, Armstrong P, Stevens D B, Bamshad M

Abstract excerpt

PURPOSE: To identify the gene causing tarsal/carpal coalition syndrome (TCC). METHODS: Individuals from three kindreds with TCC and normal hearing were used to map TCC and screen for mutations in Noggin (NOG). RESULTS: Three different missense mutations in NOG were found. Two of these mutations are identical to mutations previously reported to cause proximal symphalangism (SYM1). CONCLUSIONS: TCC is allelic to...

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Source

Identifiers

PMID: 11545688
DOI: 10.1097/00125817-200109000-00004

Genes

NOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identical mutations in NOG can cause either tarsal/carpal coalition syndrome or proximal symphalangism.PMID 11545688Read ↗

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