Article
Polymorphism in the gene regulatory region of MCP-1 is associated with asthma susceptibility and severity.
The Journal of allergy and clinical immunology - 1 Sept 2001
Szalai C, Kozma G T, Nagy A, Bojszkó A, Krikovszky D, Szabó T, Falus A
Abstract excerpt
BACKGROUND: Chemokines play an important role in the pathophysiology of asthma and allergy. Recently, polymorphisms in the gene regulatory region of monocyte chemoattractant protein 1 (MCP-1) and in the promoter region of RANTES have been found; these polymorphisms increase the expression of the...
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