Article
Linkage disequilibrium at the Angelman syndrome gene UBE3A in autism families.
Genomics - 1 Sept 2001
Nurmi E L, Bradford Y, Chen Y, Hall J, Arnone B, Gardiner M B, Hutcheson H B, Gilbert J R, Pericak-Vance M A, Copeland-Yates S A, Michaelis R C, Wassink T H, Santangelo S L, Sheffield V C, Piven J, Folstein S E, Haines J L, Sutcliffe J S
Abstract excerpt
Autistic disorder is a neurodevelopmental disorder with a complex genetic etiology. Observations of maternal duplications affecting chromosome 15q11-q13 in patients with autism and evidence for linkage and linkage disequilibrium to markers in this region in chromosomally normal autism families indicate the existence of a susceptibility locus. We have screened the families of the Collaborative Linkage Study of...
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