Article
Cerebral vein thrombosis and prothrombin gene (G20210A) mutation.
Clinical neurology and neurosurgery - 1 Oct 2001
Heckmann J G, Tomandl B, Erbguth F, Neidhardt B, Zingsem H, Neundörfer B
Abstract excerpt
Recently, prothrombin gene mutation G20210A has been associated with elevated thrombosis risk and rarely with cerebral vein thrombosis (CVT). Three patients are described who had this genetic predisposition and who developed CVT in an unusual constellation with other factors. In the first patient, the intake of valproic acid (VPA) may have played an aggravating role in the development of CVT; in the second...
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