Article
Survey of factor V leiden and prothrombin gene mutations in systemic lupus erythematosus.
Clinical rheumatology - 1 Jan 2001
Topaloglu R, Akierli C, Bakkaloglu A, Aydintug O, Ozen S, Besbas N, Ozcelik T
Abstract excerpt
The two most common hereditary risk factors for thrombosis are factor V Leiden mutation and a prothrombin gene mutation. There is indeed a thrombotic tendency in patients with systemic lupus erythematosis (SLE) and it is not always associated with antiphospholipid antibodies. We aimed to determine the relationship between both factor V Leiden and prothrombin gene mutations and SLE. Using polymerase chain reaction...
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