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Ethyl Acetate Extract of the Stem Bark of Cudrania Tricuspidata Induces Apoptosis in Human Leukemia HL-60 Cells

1 Jan 2001

Abstract excerpt

Apoptosis is now widely accepted as playing a role in tumorigenesis. An effective compound which can kill tumors via apoptotic pathway appears to be a relevant strategy to suppress various human tumors. The ethyl acetate extract from the stem bark of Cudrania tricuspidata (EACT) showed dose- and time-dependent cytotoxic effects on human leukemia HL-60 cells. DNA fragmentation and morphological changes,...

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PMID: 11527073
DOI: 10.1142/s0192415x01000332

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