Article
Relative risk for cognitive impairments in siblings of patients with schizophrenia.
Biological psychiatry - 15 Jul 2001
Egan M F, Goldberg T E, Gscheidle T, Weirich M, Rawlings R, Hyde T M, Bigelow L, Weinberger D R
Abstract excerpt
BACKGROUND: Patients with schizophrenia have impairments in several domains of cognition, including working memory/executive function, verbal memory, language, oculomotor scanning/psychomotor speed, and general intelligence. Impairments have also been found in unaffected siblings, suggesting they could be heritable. To assess the suitability of cognitive dysfunction for use in genetic studies, we estimated...
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