Article
[Changes in hemostasis system in patients with hereditary thrombophilia caused by mutation of blood coagulation factor V ( factor V Leiden)].
Terapevticheskii arkhiv - 1 Jan 2001
Papaian L P, Kobilianskaia V A, Sheĭdina A M, Baranovskaia S S, Sirotkina O V, Kargin V D, Saltykova N B, Beliazo O E, Golovina O G, Papaian K A, Tarkovskaia L R
Abstract excerpt
AIM: To study the incidence of mutation of Leyden's factor V in patients with venous thrombosis and the hemostatic system in carrier of this genetic defect. MATERIALS AND METHODS: A hundred and one patients aged 15-69 years who had venous thrombosis and 10 individuals with mutation of Leyden's factor V without manifestations in the history of thrombosis were examined. Factor V gene mutations and the thrombocyte...
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