Article
[High concentration of coagulation factor VIII as a risk factor for thrombosis].
Nederlands tijdschrift voor geneeskunde - 17 Nov 2001
Kamphuisen P W, Eikenboom H C, Rosendaal F R, Bertina R M
Abstract excerpt
Several case-control studies have shown that factor VIII levels > or = 150 IU/100 ml lead to a greatly increased risk of venous thrombosis. High levels of factor VIII are also associated with an increased risk of recurrences of thrombosis. The prevalence of high factor VIII levels is 25% in patients with a first episode of venous thrombosis and 11% among healthy controls. The contribution of high factor VIII...
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