Modifications of cellulose synthase confer resistance to isoxaben and thiazolidinone herbicides in Arabidopsis Ixr1 mutants.

doi:10.1073/pnas.191361598

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Article

Modifications of cellulose synthase confer resistance to isoxaben and thiazolidinone herbicides in Arabidopsis Ixr1 mutants.

Proceedings of the National Academy of Sciences of the United States of America - 28 Aug 2001

Scheible W R, Eshed R, Richmond T, Delmer D, Somerville C

Abstract excerpt

In many higher plants, cellulose synthesis is inhibited by isoxaben and thiazolidinone herbicides such as 5-tert-butyl-carbamoyloxy-3-(3-trifluromethyl) phenyl-4-thiazolidinone. Semidominant mutations at the IXR1 and IXR2 loci of Arabidopsis confer isoxaben and thiazolidinone resistance. Isolation of the IXR1 gene by map-based cloning revealed that it encodes the AtCESA3 isoform of cellulose synthase. The two...

Topics

Alleles
Arabidopsis
Arabidopsis Proteins
Base Sequence
Benzamides
Cloning, Molecular
DNA Primers
Drug Resistance
Gene Expression
Genes, Plant
Glucosyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Herbicides

Models, Molecular

Mutation

Plants, Genetically Modified

Thiazoles

Transformation, Genetic

Source

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Identifiers

PMID: 11517344
DOI: 10.1073/pnas.191361598
PMCID: PMC56918

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-11517344-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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