Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of base change mutations within an Escherichia coli ribosomal RNA leader region on rRNA maturation and ribosome formation.

Nucleic acids research - 15 Aug 2001

Schäferkordt J, Wagner R

Abstract excerpt

The effects of base change mutations in a highly conserved sequence (boxC) within the leader of bacterial ribosomal RNAs (rRNAs) was studied. The boxC sequence preceding the 16S rRNA structural gene constitutes part of the RNase III processing site, one of the first cleavage sites on the pathway to mature 16S rRNA. Moreover, rRNA leader sequences facilitate correct 16S rRNA folding, thereby assisting ribosomal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cold Temperature
Share to Endoribonucleases
Share to Half-Life

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Operon

Share to Ribonuclease III

Share to Ribosomes

Share to RNA Processing, Post-Transcriptional

Share to RNA Stability

Source

Open in PubMed Open full text

Identifiers

PMID: 11504877
DOI: 10.1093/nar/29.16.3394
PMCID: PMC55841

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of base change mutations within an Escherichia coli ribosomal RNA leader region on rRNA maturation and ribosome formation.PMID 11504877Read ↗

Characterization of transient RNA-RNA interactions important for the facilitated structure formation of bacterial ribosomal 16S RNA.Semantic proximity Read ↗

Mutations in 16S rRNA in Escherichia coli at methyl-modified sites: G966, C967, and G1207.Semantic proximity Read ↗

The 16S ribosomal RNA mutation database (16SMDB).Semantic proximity Read ↗

The 23S Ribosomal RNA Mutation Database (23SMDB).Semantic proximity Read ↗

Mutational analysis of the conserved bases C1402 and A1500 in the center of the decoding domain of Escherichia coli 16 S rRNA reveals an important tertiary interaction.Semantic proximity Read ↗

Modification of rRNA as a 'quality control mechanism' in ribosome biogenesis.Semantic proximity Read ↗

Functional effects of base changes which further define the decoding center of Escherichia coli 16S ribosomal RNA: mutation of C1404, G1405, C1496, G1497, and U1498.Semantic proximity Read ↗

Structure and function of the conserved 690 hairpin in Escherichia coli 16 S ribosomal RNA: analysis of the stem nucleotides.Semantic proximity Read ↗

The effects of disruptions in ribosomal active sites and in intersubunit contacts on ribosomal degradation in Escherichia coli.Semantic proximity Read ↗

Phenotypic heterogeneity of mutational changes at a conserved nucleotide in 16 S ribosomal RNA.Semantic proximity Read ↗

Mutational analysis of 23S ribosomal RNA structure and function in Escherichia coli.Semantic proximity Read ↗

Mutations in domain V of the 23S ribosomal RNA of Bacillus subtilis that inactivate its protein folding property in vitro.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.