Article
Regaining chondrocyte phenotype in thermosensitive gel culture.
The Anatomical record - 1 Aug 2001
An Y H, Webb D, Gutowska A, Mironov V A, Friedman R J
Abstract excerpt
Chondrocyte tissue engineering continues to be a challenging problem. When chondrocytes are duplicated in vitro, it is imperative to obtain an adequate number of cells of optimal phenotype. A temperature-sensitive polymer gel, a copolymer of poly(N-isopropylacrylamide) and acrylic acid (PNiPAAm-co-Aac), has the ability of gelling at 37 degrees C (the lower critical solution temperature, LCST) or above and...
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