Article
[Two-step interferon rebound therapy for refractory chronic hepatitis C].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 2001
Kato M, Yuki N, Kaneko A, Yamamoto K, Kasahara A, Masuzawa M, Hayashi N
Abstract excerpt
In almost all patients in whom interferon(IFN) treatment dose not result in persistent negative findings for HCV-RNA, HCV-RNA levels show a rebound after discontinuing the administration. In most patients, HCV-RNA levels after administration are increased compared to pretreatment values. When a rapid increase in HCV-RNA levels causes transient exacerbation of transaminase levels, HCV-RNA levels then rapidly...
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