Article
Efficacy of interferon alpha-2b induction therapy before retreatment for chronic hepatitis C.
Liver international : official journal of the International Association for the Study of the Liver - 1 Oct 2007
Carr Catherine, Hollinger F Blaine, Yoffe Boris, Wakil Adil, Phillips Jason, Bzowej Natalie, Leung Janet, Mirro Katherine, Poordad Fred, Moore Dan H, Gish Robert G
Abstract excerpt
BACKGROUND/AIMS: Chronic hepatitis C (HCV) patients who have failed previous treatment have low sustained viral response (SVR) rates with repeat treatment. We evaluated whether interferon (IFN) induction during retreatment improves response rates. METHODS: Two randomized, controlled trials were conducted in chronic HCV patients who failed IFN. In Study 1, patients received IFN 3 MU daily plus ribavirin (RBV) 1000...
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