Article
[Value of high-dose interferon-alpha in chronic viral hepatitis C patients non-responder to a 1st treatment. Pilot study prospective and randomized trial].
Gastroenterologie clinique et biologique - 1 Jan 1997
Rolachon A, Kézachian G, Causse X, Baud M, Leroy V, Maynard-Muet M, Pasquier D, Zarski J P
Abstract excerpt
OBJECTIVES: The aim of this study was to evaluate the efficacy of two different doses of alpha interferon (IFN) for retreatment in chronic hepatitis C patients who were non responders to initial treatment by IFN at a dose of 3 MIU TIW for 6 months. METHODS: This open, pilot, prospective, randomized and bicentric study included patients with biopsy-proven chronic hepatitis C. Non response was defined as serum ALT...
Topics
- Adult
- Antiviral Agents
- Dose-Response Relationship, Drug
- Female
- Genotype
- Hepacivirus
- Hepatitis C, Chronic
- Humans
- Interferon alpha-2
- Interferon-alpha
- Liver
- Male
- Prospective Studies
- RNA, Viral