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Hot news: temperature-sensitive humans explain hereditary disease.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Aug 2001

Friedberg E C

Abstract excerpt

The skin-cancer-prone hereditary disease xeroderma pigmentosum is typically characterized by defective nucleotide excision repair (NER) of DNA. However, since all subunits of the core basal transcription factor TFIIH are required for both RNA polymerase II basal transcription and NER, some mutations affecting genes that encode TFIIH subunits can result in clinical phenotypes associated with defective basal...

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PMID: 11494313
DOI: 10.1002/bies.1094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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